The N.F.L. has two remaining unbeaten teams: the reliably talented New England Patriots and the underdogs in San Francisco.

Through six weeks of the season, Russell Wilson is playing the best football of his career and a leading candidate for NFL MVP. On Sunday, Wilson put together yet another near-flawless performance, leading the Seattle Seahawks to a 32-28 comeback victory over…

Lamar Jackson rolled over Cincinnati, the 49ers stayed undefeated, and the Jets, Redskins and Cardinals all, somehow, won.

49ers are undeniably team to beat in NFC West Niners Wire Robert Saleh: 49ers Defense is 'Relentless' San Francisco 49ers 49ers defense smothers Rams in 20-7 win NBCSports.com Jimmy Garoppolo Keeps the 49ers Undefeated! | 2019 NFL Highlights NFL 49ers at Rams…

In 2018, the San Francisco 49ers were an injury-ravaged mess of a football team that won just four games and finished 13th in the NFL in total defense and 28th in scoring defense...

The San Francisco 49ers travel to LA this Sunday where they'll face a ticked-off Rams team that can't wait to deliver them their first loss.

Richard Sherman accused Baker Mayfield of refusing to shake his hand before kickoff of the Browns-49ers game on Monday night. Video later appeared to show Mayfield and Sherman shaking hands at midfield, making Sherman's initial claim quite confusing. While Sh…

The San Francisco 49ers are 4-0 for the first time since 1990, and the Jimmy Garoppolo vs. Joe Montana debate is raging on NFL Twitter.

The San Francisco 49ers could be without a key piece of their offensive attack for an extended period. Fullback Kyle Juszczyk was initially diagnosed with an MCL injury sustained Monday night, per Tom Pelissero.

The San Francisco 49ers announced Tuesday afternoon that fullback Kyle Juszczyk will be out 4 to 6 weeks after suffered an MCL sprain during Monday's 31-3 shellacking of the Browns

The San Francisco 49ers could be without a key piece of their offensive attack for an extended period. Fullback Kyle Juszczyk was initially diagnosed with an MCL injury sustained Monday night, per Tom Pelissero.

Against the undefeated San Francisco 49ers on Monday night, quarterback Baker Mayfield had his worst game of the season. Mayfield's goal now is to find consistency where there's been none.

"What are the 49ers?" The rhetorical question was posed by ESPN play-by-play man Joe Tessitore midway through the third quarter of Monday night's 31-3 San Francisco victory over the Cleveland Browns...

San Francisco (4-0) secured its fourth win in as many tries by routing the Cleveland Browns (2-3), 31-3, on "Monday Night Football" in Week 5.

San Francisco 49ers defensive tackle D.J. Jones stepped away from his pregame preparation on Monday to propose to his girlfriend.

Richard Sherman doesn't think the grass is greener outside of San Francisco. "I think we're good with what we have," the 49ers cornerback said Thursday, according to NBC Sports ...

Jaguars linebacker Myles Jack was ejected Sunday against the Chiefs for throwing a punch at WR Demarcus Robinson; 49ers LB Kwon Alexander was DQ'd for a helmet-to-helmet hit.

After suffering a significant ankle sprain early in training camp, 49ers rookie defensive end Nick Bosa is slated to play in Week 1, according to NFL Network Insider Ian Rapoport.

Colin Kaepernick ’s still got it if video of his latest workout is any indication. The former San Francisco 49ers quarterback shared a video of his workout with Cleveland Browns wide receiver Odell Beckham Jr...

Jones leads Chargers past 49ers 27-24 in preseason finale

Jimmy Garoppolo exorcised his demons at Arrowhead Stadium on Saturday night with 188 yards, one touchdown and no interceptions on 14-of-20 passing in the San Francisco 49ers' 27-17 win over the Kansas City Chiefs...

While most of the NFL world loves the preseason because it builds anticipation for the start of the real games, it's also a nerve-wracking period for players fighting to make a team's roster...

Identifying and organizing the top 100 players in 49ers history.

Jay-Z was shocked that his involvement with the NFL was being interpreted by some as an affront to Colin Kaepernick.

Free-agent wide receiver Michael Crabtree has signed a one-year contract with the Arizona Cardinals , the team announced Wednesday night...

RT @49erswebzone: ICYMI: Recap: Jimmy Garoppolo and #49ers beat Chiefs 27-17, improve to 3-0 in preseason [@PeterPanacy] https://t.co/doNAh…

RT @mercnews: 49ers 27, Chiefs 17: Top takeways from Garoppolo’s bounce-back game https://t.co/4ucX4uXYzk

Preseason means nothing? Well it must mean something, because we're definitely going to the Super Bowl. https://t.co/bZR67eS6Gi

RT @RealDonalDrumpf: A chart is circulating that shows job growth in my first 30 months was 15% LOWER than the last 30 months of Obama’s “r…

What People Are Talking About Now ? Andrew Luck College football Lamar Miller What to watch Vikings 49ers #trends = https://t.co/Thdc19FZFg

RT @MattBarr_: This is coach speak for, “We’re going to showcase CJB so that we can fleece the Colts into overpaying for him.” #49ers #49wz…

13 Takeaways from 49ers 27-17 Win Over Chiefs https://t.co/onNFB4gc61

Richie James has played his way onto the #49ers roster, right? I can’t imagine how they let him go.

RT @NFL: FINAL: @49ers WIN in Arrowhead! #SFvsKC https://t.co/1Rh7EdMcOW

RT @NFL: FINAL: @49ers WIN in Arrowhead! #SFvsKC https://t.co/1Rh7EdMcOW

RT @LakersGotNow: It’s not even up for debate lakers have the best team in the league . Imagine taking it to the rim with AD & Howard in th…

8/24/19 Recap 4-8 day, -17.39 units!! NFLX 25-16-1 +13.4 units August 139-124-2, -15.49 units Just a shitty day minus the 49ers win and cover. Back to the grind $50/month starting 9/1, $200 through the Super Bowl. DM for details.

RT @49ersESP: FINAL: SF 27 - KC 17 #49ers #Los49ers #SFvsKC https://t.co/0BAgmUM0Mr

RT @TheAthleticSF: Five observations from a 49ers win: Jimmy Garoppolo returns strong, Kyle Shanahan says he plans to carry 3 quarterbacks.…

Had to record the 49ers game. Jimmy G looked much better. Brieda is the clear no. 1 back. Gotta get Deebo more involved. Defense is still yiiiiiiikes.

Three non Garoppolo-related takeaways from the #49ers encouraging preseason game in KC https://t.co/B7JbzhIXGR

RT @HtownBetterr: Didn’t think I would have to post this, but I saw some confused people on the TL. https://t.co/2V2UG5nICF

RT @mikeyBcards: I've got an inexpensive break tonight too! 1 Box of Origins, Pick your team, get 3 random teams free! Cardinals randomed t…

RT @fourth_nine: Mitch Wishnowsky showing off his massive leg again. #49ers https://t.co/eNV03gkpcu

RT @Chiefs: Best of luck this season, @49ers! https://t.co/cgLYERXIdp

Nfl:Brees breezes for TD in only series, Saints top Jets 28-13> Dre... https://t.co/98X9scGHOY #nfl https://t.co/knWBwYFrNQ

#49ers roster: Kyle Shanahan plans to keep 3 QBs [@TheNinersWire, @KyleAMadson] https://t.co/tlACZKJShO

8 #49ers whose stock went up in win over Chiefs [@TheNinersWire, @KyleAMadson] https://t.co/uwkfKHWAe7

Stock report: 8 #49ers see their stock rise in Saturday's win over the Chiefs. https://t.co/m5nELAEi68

Stock report: 8 #49ers see their stock rise in Saturday's win over the Chiefs. https://t.co/YKx9OlXRFD

Stock report: 8 #49ers see their stock rise in Saturday's win over the Chiefs. https://t.co/vPU4G4Oc1v

Shanahan: 49ers plan to keep Garoppolo, Mullens and Beathard https://t.co/8Oo8glAdEb

RT @49ers: 3-0 heading into the preseason finale! #SFvsKC https://t.co/xJ4LAzuCfS

Saturday's NFL: Garoppolo, Mahomes both sharp as 49ers top Chiefs. https://t.co/onUcPXuIJV https://t.co/ar9nRc2xtF

RT @49erswebzone: Jeff Wilson improves chances for a roster spot in #49ers' win vs. Chiefs [@PeterPanacy] https://t.co/26156gCusz

RT @missagay: @lynn_mansir @apiercingtruth @bsnead4646 @ChloePolitiCat @BobDarrin @jakalpimp @JoyEdgar4 @SerenityDharma @wally_polischuk @k…

With the abundance of having good players at multiple positions, RB, DL and WR (maybe) the #49ers should be looking to trade for an interior OL because I doubt any of them hit the waiver wire. Post your trades. #NB9ers

Bernie Sanders coming up on CNN

RT @DeciderDivider: @missagay @JoyEdgar4 @apiercingtruth @bsnead4646 @ChloePolitiCat @BobDarrin @jakalpimp @lynn_mansir @SerenityDharma @wa…

New trending GIF tagged sports, football, sport, nfl, 2019, flex, sf, san francisco, 49ers, san francisco 49ers, preseason, flex on em, marquise, marquise goodwin via Giphy https://t.co/gjOv87hCuW https://t.co/Eok18lSXJD

RT @Chiefs: Best of luck this season, @49ers! https://t.co/cgLYERXIdp

RT @NFL: Jimmy Garoppolo lofts it up and @MattBreida lays out for the @49ers TD! @JimmyG_10 | #SFvsKC https://t.co/oEcnPG3Kmq

New Awsome GIF. Tags: sports, football, sport, nfl, 2019, flex, sf, san francisco, 49ers, san francisco 49ers, preseason, flex on em, marquise, marquise goodwin https://t.co/54GJYXSbSE

RT @Rob_Lowder: Jimmy Garoppolo’s first half against the Chiefs: Five series 14 of 20 70% completion 188 yards 1 touchdown 116.2 QB rating…

RT @49ers: 3-0 heading into the preseason finale! #SFvsKC https://t.co/xJ4LAzuCfS